Premier League clubs are preparing for a major mid-season disruption as many African players are expected to depart for the Africa Cup of Nations, set to take place in Morocco from 21 December 2025 to 18 January 2026.
Top-flight teams across England will be impacted, with key players from Liverpool, Manchester United, Fulham, Nottingham Forest, and other clubs set to miss several crucial fixtures during the busy winter period.
Among the biggest absentees is Liverpool’s Mohamed Salah, Egypt’s star forward, who is likely to miss up to six Premier League matches, including high-profile clashes against Tottenham, Arsenal, and Fulham.
Manchester United will also feel the loss of Bryan Mbeumo, Noussair Mazraoui, and Amad Diallo, while Fulham faces the absence of three Nigerian internationals: Calvin Bassey, Alex Iwobi, and Samuel Chukwueze.
Other clubs affected include Nottingham Forest, missing Ola Aina, Willy Boly, and Ibrahim Sangaré, and Tottenham Hotspur, who will lose Pape Matar Sarr, Yves Bissouma and Mohammed Kudus.
AFCON 2025 is expected to be a test of squad depth for Premier League clubs, as teams will have to navigate the congested winter fixture schedule without some of their key African internationals.
Here are other players expected at AFCON 2025.
Aston Villa Evann Guessand Ivory Coast
Brentford Dango Ouattara Burkina Faso
Brentfod Frank Onyeka Nigeria
Burnley Lyle Foster South Africa
Burnley Hannibal Mejbri Tunisia
Crystal Palace Christantus Uche Nigeria
Everton Iliman Ndiaye, Senegal
Everton Idrissa Gueye Senegal
Manchester City Omar Marmoush Egypt
Manchester City Rayan Aït-Nouri Algeria
West Ham El Hadji Malick Di
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